Greener Friedel-Crafts Acylation Using Microwave-Enhanced Reactivity of Bismuth Triflate in the Friedel-Crafts Benzoylation of Aromatic Compounds with Benzoic Anhydride

friedel–crafts acylation of aromatic compounds

an efficient method for the friedel–crafts acylation of a wide range of aromatic compounds in good to excellent yields under solvent-free conditions, using iron zirconium phosphate (zpfe) was investigated. the catalyst is easy to prepare and shows interesting catalytic properties. the catalyst was characterized by some instrumental techniques such as xrd, icp-oes, sem and tem. a wide variety of...

Biocatalytic Friedel–Crafts Acylation and Fries Reaction

The Friedel-Crafts acylation is commonly used for the synthesis of aryl ketones, and a biocatalytic version, which may benefit from the chemo- and regioselectivity of enzymes, has not yet been introduced. Described here is a bacterial acyltransferase which can catalyze Friedel-Crafts C-acylation of phenolic substrates in buffer without the need of CoA-activated reagents. Conversions reach up to...

Friedel–Crafts acylation of 2-methoxynaphthalene over zeolite catalysts

The Friedel–Crafts acylation of 2-methoxynaphthalene was carried out in the liquid-phase batch conditions using Hmordenite, H-beta and H-Y zeolite as catalysts. All the catalysts showed 35–40% conversion in the temperature range of 100–150◦C. 1-Acyl-2-methoxynaphthalene was formed as the primary product. When acetyl chloride was used as the acylating agent, a higher yield of 6-acyl-2-methoxynap...

Fisher Title : Bismuth Triflate Catalyzed Friedel - Crafts Acylations of Sydnones Date : June 2005

In the present work, suitably functionalized arylsydnones were used to synthesize a variety of 4-acyl-sydnones and diacyl sydnones, both as potential precursors to novel sydnoquinolines. The approach to the diacyl species is based on the discovery that activated sydnones brominate in both the 4 position of the sydnone ring and on the phenyl ring. Thus, it seemed likely that Friedel-Crafts react...

Friedel-Crafts alkylation of Phenol using Ionic Liquid as Catalyst